| First Author | Nadella KM | Year | 2016 |
| Journal | Nat Methods | Volume | 13 |
| Issue | 12 | Pages | 1001-1004 |
| PubMed ID | 27749836 | Mgi Jnum | J:349643 |
| Mgi Id | MGI:6391804 | Doi | 10.1038/nmeth.4033 |
| Citation | Nadella KM, et al. (2016) Random-access scanning microscopy for 3D imaging in awake behaving animals. Nat Methods 13(12):1001-1004 |
| abstractText | Understanding how neural circuits process information requires rapid measurements of activity from identified neurons distributed in 3D space. Here we describe an acousto-optic lens two-photon microscope that performs high-speed focusing and line scanning within a volume spanning hundreds of micrometers. We demonstrate its random-access functionality by selectively imaging cerebellar interneurons sparsely distributed in 3D space and by simultaneously recording from the soma, proximal and distal dendrites of neocortical pyramidal cells in awake behaving mice. |
