Primary Identifier | MGI:3809312 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Hcn4 |
Transmission | Germline | Strain of Origin | Not Specified |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A cre/ERT2 fusion gene and a neo cassette were inserted into exon 1 downstream of the translation initiation codon. Expression is tamoxifen inducible and localized to the superior vena cava in the proximity of the right atrial appendage and the aorta, specifically in the sinoatrial and atrioventricular nodes. |