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Allele : Tradd<tm1.1Zgl> TNFRSF1A-associated via death domain; targeted mutation 1.1, Zhenggang Liu

Primary Identifier  MGI:3810080 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tradd
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed and FRT flanked neo cassette was inserted in intron 2 and a third loxP site was inserted 3' of exon 5. Mice carring this floxed allele were then crossed to mice carrying Tg(EIIa-cre)C5379Lmgd to excise exons 3-5 which code for amino acid residues 51-310. This results in the deletion of the interactin domains for TRAF2 and RIP (receptor interacting domain).
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele