Primary Identifier | MGI:3810438 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(THY1-SNCA*A30P)M30Sud |
Strain of Origin | (C57BL/6J x SJL/J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene construct contains the human A30P mutant SNCA (synuclein, alpha) gene under the control of a human THY1 (thymus cell antigen 1, theta) promoter. Expression of the transgene is 5-fold higher in the brain and 10-fold higher in the spinal cord. |