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Allele : Gpx4<tm2Marc> glutathione peroxidase 4; targeted mutation 2, Marcus Conrad

Primary Identifier  MGI:3810783 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gpx4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 5-7 encoding the Sec-insertion sequence element and the polyadenylation signal were flanked by loxP sites. A frt-flanked neomycin resistance cassette was placed immediately downstream of the 3' loxP site. Founder mice were crossed with FLPe deleter mice to remove the neomycin cassette leaving behind a single frt site. Correct targeting was confirmed by Southern blotting.
  • mutations:
  • Insertion
  • synonyms:
  • Gpx4<flox>,
  • Gpx4<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

22 Publication categories