Primary Identifier | MGI:3812340 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Cxadr |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1, which contains the translation start, was replaced with a floxed exon 1 and an upstream FRT-flanked neomycin resistance cassette. The neomycin resistance cassette was removed by germline expression of the FLP recombinase after targeting. Upon expression of cre recombinase, exon 1 is excised creating a null allele. |