| Primary Identifier | MGI:3811855 | Allele Type | Chemically induced (ENU) |
| Gene | Slc2a1 | Inheritance Mode | Dominant |
| Strain of Origin | C57BL/6JJcl | Is Recombinase | false |
| Is Wild Type | false | Project Collection | RIKEN GSC ENU Project |
| molecularNote | This mutation was identified in an ENU mutagenesis screen. Sequence analysis of the gene revealed a T-to-C mutation in exon 7. The mutation resulted in a substitution of serine with proline at residue 324 of the encoded protein. RT-qPCR analysis showed a significant increase of Slc2a1 mRNA expression in the forebrain of adult heterozygotes. Immunoblotting showed no significant alterations of SLC2A1 protein expression in the forebrain of adult heterozygotes relative to wild-type controls. |
