Primary Identifier | MGI:3817457 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Isl1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4, which encodes the homeodomain of the protein product, was floxed by the insertion of a loxP site on one end and a loxP site and frt-flanked neo cassette on the other end. After germline integration, the frt-flanked neo cassette was removed from Isl1tm4Sev by crossing with FLPe transgenic strain. |