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Allele : Six3<tm3Gco> sine oculis-related homeobox 3; targeted mutation 3, Guillermo Oliver

Primary Identifier  MGI:3814869 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Six3
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A single bp transition (T749C) was introduced into the first exon. This causes a valine to alanine change at amino acid residue 250. In addition, a floxed cassette containing a stop codon and a neomycin resistance gene was inserted upstream of the first exon thus inactivating the knocked-in mutation.
  • mutations:
  • Insertion
  • synonyms:
  • Six3<cki>,
  • Six3V250,
  • Six3V250,
  • Six3<cki>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories