Primary Identifier | MGI:3817238 | Allele Type | Targeted |
Attribute String | Modified regulatory region | Gene | Mesp2 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Two Tbx6 binding sites contained within the minimal pre-somitic mesoderm enhancer region upstream of exon 1 were replaced with ones containing mutations at site B and site D. A floxed neo cassette inserted upstream of the enhancer region was removed by germ line, cre mediated recombination. |