| Primary Identifier | MGI:3817480 | Allele Type | QTL |
| Gene | Azdm1 | Inheritance Mode | Other (see notes) |
| Strain of Origin | A/J | Is Recombinase | false |
| Is Wild Type | false |
| description | Azdm1 is a modifier of Tg(PRNP-APPSweInd)8Dwst. Amyloid plaque number and amyloid burden traits exhibit additive inheritance while brain amyloid-beta 40 and amyloid-beta 42 traits exhibit codominant inheritance. |
| molecularNote | This allele confers decreased amyloid brain plaque number, decreased amyloid burden, and decreased levels of brain amyloid-beta 40 and amyloid-beta 42 compared to C57BL/6J. |
