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Allele : Azdm4<A/J> Alzheimer's disease modifier 4; A/J

Primary Identifier	MGI:3818005	Allele Type	QTL
Gene	Azdm4	Inheritance Mode	Other (see notes)
Strain of Origin	A/J	Is Recombinase	false
Is Wild Type	false

description	Azdm4 is a modifier of Tg(PRNP-APPSweInd)8Dwst and exhibits additive inheritance.
molecularNote	This allele confers decreased amyloid plaque number compared to C57BL/6J.

earliestPublication:
Sebastiani G, et al. (2006) Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice. Hum Mol Genet 15(15):2313-23

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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