| Primary Identifier | MGI:3818574 | Allele Type | Gene trapped |
| Attribute String | Hypomorph | Gene | Atg16l1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Sanger Inst. Gene Trap Res. |
| molecularNote | A gene-trap vector containing a splice acceptor followed by a beta-geo cassette disrupted the gene locus by inserting within the intronic region after exon 6. Protein expression of both the alpha and beta isoforms of the gene product were 23-37% of wild-type as determined by immunoblots of ileal lysates from homozygous mice. This is a hypomorphic allele. |
