| Primary Identifier | MGI:3817966 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hsd11b1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed neo cassette was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Cre-mediated recombination removed the neo cassette and exon 5. RT-PCR confirmed the absence of transcript expression in the liver, tibialis anterior amd soleus. The absence of enzymatic activity was confirmed. |
