|  Help  |  About  |  Contact Us

Allele : Aicda<tm4Mnz> activation-induced cytidine deaminase; targeted mutation 4, Michel C Nussenzweig

Primary Identifier  MGI:3818467 Allele Type  Targeted
Gene  Aicda Transmission  Germline
Strain of Origin  B6(Cg)-Tyr<c-2J>/J Is Recombinase  false
Is Wild Type  false
molecularNote  The threonine at amino acid position 140 was mutated to an alanine (T140A) by targeted recombination of exon 3. A loxP-flanked neomycin selection cassette was inserted between exons 2 and 3. Immunoblotting of B cell extracts indicated expression of the mutated protein was similar to that of the endogenous protein.
  • mutations:
  • Nucleotide substitutions,
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • AID<T140A>,
  • AID<T140A>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories