| Primary Identifier | MGI:3819391 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Telo2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Transient cre expression in ES cells was used to remove the floxed exon 3 and the neo cassette. This deletion results in a frame shift and premature termination of translation at amino acid 168 of 840. A two-fold reduction in protein expression levels was confirmed by western blot analysis on embryonic fibroblasts heterozygous for the allele. |
