| Help | About | Contact Us

Allele : Pak6<tm1Amin> p21 (RAC1) activated kinase 6; targeted mutation 1, Audrey Minden

Primary Identifier	MGI:3821622	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Pak6
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

All of exon 1 and part of exon 2 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Nekrasova T, et al. (2008) Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion. Dev Biol 322(1):95-108

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

5 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74721014

MouseMine