| Primary Identifier | MGI:3819843 | Allele Type | Targeted |
| Gene | Smad4 | Transmission | Germline |
| Strain of Origin | 129S/SvEv-Gpi1<c> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Leucine 146 and Leucine 148 encoded by exon 4 were mutated to glycine and alanine respectively. A floxed PGK-hygro cassette was introduced into intron 4. Transient expression of cre recombinase subsequently removed the selection cassette from correctly targeted ES cells. |
