| Help | About | Contact Us

Allele : Tg(CAG-cat,-Ptpn11)1Rbns transgene insertion 1, Jeffrey Robbins

Primary Identifier	MGI:3822130	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(CAG-cat,-Ptpn11)1Rbns
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

The ubiquitous CAG (chicken beta actin) promoter was used to drive cre-dependent expression Ptpn11 following removal of an intervening floxed chloramphenicol (cat) gene. Several lines were created with similar expression patterns. (No line names given)

mutations:
Insertion

synonyms:
CAGCAT-WT-Shp2,
CAGCAT-WT-Shp2

earliestPublication:
Krenz M, et al. (2008) Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome. Proc Natl Acad Sci U S A 105(48):18930-5

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74721426

MouseMine