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Allele : Tg(Myh7-Ptpn11*Q79R)11Rbns transgene insertion 11, Jeffrey Robbins

Primary Identifier  MGI:3822132 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh7-Ptpn11*Q79R)11Rbns
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The promoter was used to drive expression of Ptpn11 containing the amino acid substitution of arginine for glutamine at position 79 in the fetal heart. This mutation results in an increase in phosphatase activity. Several lines were created and line 11 was used in subsequent experiments. Line 14 expresses the transgene at lower levels than line 11.
  • mutations:
  • Insertion
  • synonyms:
  • beta-MHC-Q97R11,
  • beta-MHC-Q97R11
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories