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Allele : Ifnar1<m1Btlr> interferon (alpha and beta) receptor 1; mutation 1, Bruce Beutler

Primary Identifier  MGI:3822164 Allele Type  Chemically induced (ENU)
Gene  Ifnar1 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  The mutant phenotype was discovered in a screen of macrophages from G3 progeny of an ENU mutagenized male mouse for their ability to control viral infection. The mutation has been identified as an A to C transversion at nucleotide position 1150 (Genbank: NM_010508), in the eighth of the gene's 11 exons. It results in replacement of threonine by proline at amino acid position 341 of the protein (T341P), in its extracellular domain.
  • mutations:
  • Single point mutation
  • synonyms:
  • macro-1,
  • macro-1
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories