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Allele : Tg(APOE-DHCR7)2Hoyu transgene insertion 2, Hongwei Yu

Primary Identifier	MGI:3819682	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(APOE-DHCR7)2Hoyu
Strain of Origin	C57BL x FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

The human promoter was used to drive liver-specific expression of the human gene. Two lines were created (line 2 and line 3) with identical patterns of expression.

mutations:
Insertion

synonyms:
TgDHCR7-2,
TgDHCR7-2

earliestPublication:
Yu H, et al. (2007) Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice. BMC Dev Biol 7:27

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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