Primary Identifier | MGI:3822026 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Bmp2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 3 and an frt flanked neo cassette, second loxP site, and a human alkaline phosphatase gene were inserted in the 3' UTR of exon 3. Quantitative RT-PCR indicated a decrease in RNA expression in homozygous embryos. |