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Allele : Tg(Ly6a-SET/NUP214)2969Gcg transgene insertion 2969, Gerard C Grosveld

Primary Identifier  MGI:3822861 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ly6a-SET/NUP214)2969Gcg
Strain of Origin  FVB/NJ Is Recombinase  false
Is Wild Type  false
molecularNote  The mouse promoter was used to drive early hematopoietic cell-specific expression of human SET intron 7-8 fused to NUP214 intron 17-18. This fusion mimics the human translocation t(9,9)(q32;34) identified in patients with acute undifferentiated leukemia. Three lines were created (2945, 2969, and 2971) with line 2969 selected as the representative line.
  • mutations:
  • Insertion
  • synonyms:
  • SET-CAN,
  • SET-CAN
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories