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Allele : Gt(ROSA)26Sor<tm1(Hesx1)Jpmb> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Juan Pedro Martinez Barbera
Primary Identifier  MGI:3822482 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  The Hesx1 coding sequence was cloned into a vector containing a floxed cassette with a PGK-Neo selection marker and a tpA transcriptional stop sequence. By homologous recombination, this construct was inserted into the Gt(ROSA)26Sor locus. The loxP site orientations were inverted to avoid translation interference due to the presence of an ATG within the loxP sites. Upon Cre-mediated excision of the selection cassette/stop sequence, Hesx1 is transcribed under control of the Gt(ROSA)26Sor promoter.
  • mutations:
  • Insertion
  • synonyms:
  • R26<Cond-Hesx1>,
  • R26<Cond-Hesx1>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories





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