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Allele : Fgfr3<tm2Schl> fibroblast growth factor receptor 3; targeted mutation 2, Joseph Schlessinger

Primary Identifier  MGI:3823026 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fgfr3
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin expression cassette was inserted into intron 9 and a stop codon was inserted in exon 9. This results in an incomplete and misfolded D3 segment in the mesenchymal or c isoform. Chimeric mice were mated to Tg(ACTB-cre)2Mrt mice to excise the floxed neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Fgfr3c<->,
  • Fgfr3c<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories