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Allele : Adar<tm1.1Phs> adenosine deaminase, RNA-specific; targeted mutation 1.1, Peter H Seeburg

Primary Identifier  MGI:3828307 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Adar
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo selection cassette was placed upstream of exon 7 in the SmaI restriction site and an additional loxP site was inserted downstream of exon 9. Correct targeting was confirmed by genomic PCR. LoxP-flanked (floxed) sequence encoded residues 707?870 of the interferon-inducible form of ADAR1 (GenBankTM/EBI accession number AAK16102), including essential regions for editing activity.
  • mutations:
  • Insertion
  • synonyms:
  • adar<f7-9>,
  • adar<f7-9>,
  • Adar<f>,
  • Adar<f>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

22 Publication categories