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Allele : Cftr<tm1.1Cwr> cystic fibrosis transmembrane conductance regulator; targeted mutation 1.1, Case Western Reserve University

Primary Identifier  MGI:3822761 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cftr
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Germ line, cre mediated recombination was used to remove exon 11 (exon 10 in legacy nomenclature numbering). Absence of full-length transcript expression was confirmed by RT-PCR on lung and intestine extracts. Expression of a smaller than normal transcript is observed.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cftr<delta10>,
  • Cftr<delta10>,
  • Cftr<delta10>Exon11,
  • Cftr<delta10>Exon11
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories