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Allele : Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt transgene insertion 1, Gail R Martin

Primary Identifier  MGI:3829033 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  This transgene has been mapped to Chromosome 2, ~10 cM from Grem1. (J:94077)
molecularNote  This transgene consists of a CAG promoter followed by a floxed beta geo cassette, a mouse sprouty 2 cDNA, an IRES, and a human placental alkaline phosphatase cDNA. In the absence of Cre mediated recombination only lacZ is expressed. Following Cre mediated recombination Spry2 and ALPP are expressed.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(CAG-lacZ,-Spry2,-ALPP)1Mrt,
  • Tg(CAG-lacZ,-Spry2,-ALPP)1Mrt,
  • Spry2-GOF,
  • Spry2-GOF
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories