| Primary Identifier | MGI:3829038 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Pcdha |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An in-frame termination codon followed by a floxed neomycin resistance gene cassette was inserted at the first codon of the fourth exon, which encodes a subtype-specific region of isoform B. Germ line cre-mediated recombination was used to remove the neo cassette. The absence of isoform B protein expression was confirmed by western blot analysis on brain extracts. Expression of isoform A protein is unaffected. |
