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Allele : Alx4<Lst-2J> aristaless-like homeobox 4; Strong's luxoid 2 Jackson

Primary Identifier	MGI:3829369	Allele Type	Spontaneous
Attribute String	Null/knockout	Gene	Alx4
Inheritance Mode	Semidominant	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false

molecularNote

The mutation is a a 33.4 Kb deletion encompassing the 5' region and exon 1 of the gene. Immunostaining of coronal sections of E14.5 embryo heads showed that no detectable protein is expressed from this allele.

mutations:
Intragenic deletion

synonyms:
Nm3768,
Alx4<->,
Alx4<->,
Nm3768

earliestPublication:
Curtain M, et al. (2015) A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice. Mamm Genome 26(3-4):173-80

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

6 Publication categories

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