Primary Identifier | MGI:3829429 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Cyp1a1-cre/ERT)1Dwi |
Strain of Origin | (CBA x C57BL/6)F1 | Induced With | tamoxifen and beta-naphthoflavone |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The rat Cyp1a1 promoter was used to drive the expression of a cre/ERT fusion that is inducible and dose-dependent. Cre expression in various tissues (small intestine, liver, bladder, stomach, esophagus, and gall bladder) is only achieved following treatment with tamoxifen and beta-naphthoflavone. Two lines were created with identical expression patterns. |