| Primary Identifier | MGI:3830330 | Allele Type | Targeted |
| Attribute String | RMCE-ready | Gene | Lrp1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Recombination-mediated cassette exchange (RMCE) was used to replace exons 76 through 89 with an frt-flanked cassette containing a cDNA for exons 76 through 89 and a floxed neo gene. The cDNA contains mutations in exon 76 that result in amino acid substitutions of RHRR with AHAA and disrupt the furine cleavage site. |
