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Allele : Fgfr3<tm1.1Aomw> fibroblast growth factor receptor 3; targeted mutation 1.1, Andrew O M Wilkie

Primary Identifier	MGI:3831364	Allele Type	Targeted
Attribute String	Humanized sequence	Gene	Fgfr3
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A point mutation changing a C to G at position 731 in exon 7 (P244R) and a floxed neo cassette in intron 7 were introduced by homologous recombination. The neo cassette was then removed by Cre mediated recombination.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Fgfr3<P244R>,
Fgfr3<P244R>

earliestPublication:
Mansour SL, et al. (2009) Hearing loss in a mouse model of Muenke syndrome. Hum Mol Genet 18(1):43-50

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

6 Carried By

0 Driven By

8 Publication categories

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