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Allele : Tg(CMV-PRKR)1Wcl transgene insertion 1, Warren C Ladiges

Primary Identifier	MGI:3830478	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(CMV-PRKR)1Wcl
Strain of Origin	(C57BL/6 x C3H)F1 x C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

cDNA encoding human eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2; previously PRKR, interferon-mediated double-stranded RNA-activated protein kinase) is expressed under control of a cytomegalovirus promoter.

mutations:
Insertion

synonyms:
Tg(CMV-PRKR)1Wcl,
Tg(CMV-EIF2AK2)1Wcl,
Tg(CMV-EIF2AK2)1Wcl,
Tg(CMV-PRKR)1Wcl

earliestPublication:
Ladiges W, et al. (2002) Expression of human PKR protein kinase in transgenic mice. J Interferon Cytokine Res 22(3):329-34

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

2 Publication categories

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