| Primary Identifier | MGI:3831172 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Pbsn-IGF1*)5305Ng |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A transgenic construct containing the human insulin-like growth factor 1 (somatomedin C) isoform, IGF-1des (that has a 3-amino acid deletion in the N terminus of the mature protein), under the control of the minimal -426/+28 rat probasin promoter, and carrying SV40 polyadenylation site sequences was injected into fertilized FVB/N mouse eggs. Three lines were generated (5299, 5305, and 6206). Founder line 5305 showed the highest expression and was characterized most thoroughly. |
