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Allele : Tg(Pbsn-IGF1*)5305Ng transgene insertion 5305, Norman M Greenberg
Primary Identifier  MGI:3831172 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Pbsn-IGF1*)5305Ng
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  A transgenic construct containing the human insulin-like growth factor 1 (somatomedin C) isoform, IGF-1des (that has a 3-amino acid deletion in the N terminus of the mature protein), under the control of the minimal -426/+28 rat probasin promoter, and carrying SV40 polyadenylation site sequences was injected into fertilized FVB/N mouse eggs. Three lines were generated (5299, 5305, and 6206). Founder line 5305 showed the highest expression and was characterized most thoroughly.
  • mutations:
  • Insertion
  • synonyms:
  • PB-Des,
  • PB Des IGF-1,
  • PB-Des,
  • IGF-1<des>,
  • PB-IGF1<des1,3>,
  • IGF-1<des>,
  • PB Des IGF-1,
  • PB-IGF1<des1,3>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

4 Publication categories

Trail: Allele




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