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Allele : Id1<tm1Xhsu> inhibitor of DNA binding 1, HLH protein; targeted mutation 1, Xiao-Hong Sun

Primary Identifier  MGI:3831561 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Id1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  An eGFP vector and a floxed neomycin cassette was knocked into the untranslated region of exon 1 of the gene locus. Founder mice were crossed with EIIa-cre transgenic mice to remove the neomycin cassette, leaving behind a loxP site. GFP expression was detected in bone marrow cells of myeloid lineages in both heterozygote and homozygote mice. Endogenous protein was not detected in immunobloting of cytokine-stimulated bone marrow cells from homozygote mice confirming this is a null allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Id1<GFP>,
  • Id1<GFP>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

12 Publication categories