|  Help  |  About  |  Contact Us

Allele : Tlr6<m3Btlr> toll-like receptor 6; mutation 3, Bruce Beutler

Primary Identifier  MGI:3831305 Allele Type  Chemically induced (ENU)
Gene  Tlr6 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  This mutation was discovered in a TLR Signaling Screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises a T to A transversion at nucleotide position 1301 of the gene (Genbank: NM_011604) that results in conversion of a triplet encoding leucine at amino acid position 190 to a termination codon (L190Ter), truncating the protein by 416 amino acids at its C terminus.
  • mutations:
  • Single point mutation
  • synonyms:
  • MALP-2 specific defect 2,
  • m2sd2,
  • msd2,
  • m2sd2,
  • MALP-2 specific defect 2,
  • msd2
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele