| Primary Identifier | MGI:3832097 | Allele Type | Spontaneous |
| Gene | Uchl1 | Strain of Origin | BALB/cJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 795 base-pair intragenic deletion resulted in the removal of the final 24 base-pairs of exon 6 and the first 771 base-pairs of intron 6. As a result of the mutation, 99 base-pairs of intron 6 are included in the mRNA and a cryptic splice donor within intron 6 is used to splice the mRNA to exon 7. The included intron 6 sequence encoded 13 novel amino acids before a premature termination codon was encountered, resulting in the loss of the final 78 amino acids of the protein. Immunoblot analysis of brain extracts failed to detect any protein. |
