| Primary Identifier | MGI:3834913 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Ext1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An inverted loxP site was introduced upstream to exon 2 in a genomic framgment containing the Ext1 gene. The fragment was then subcloned into a vector upstream of the forward-facing loxP-flanked neomycin resistance (Neo) cassette. The linearized targeti vector was electroporated into R1 ES cells. Cre-mediated recombination of this allele will result in inversion of exon2 of Ext1 and distruption of Ext1 function. |
