Primary Identifier | MGI:3832668 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Hprt1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The complete 13.5kb human AGT genomic sequence from an AA haplotype individual was inserted upstream of the Hprt locus in BK4 ES cells. The AA haplotype contains the following nucleotides at the positions indicated: -6A, -20A, -217A, -532T, -793A, -1074T. The insertion vector also restored part of the Hprt promoter and exon regions that are missing in BK4 ES cells. |