| Primary Identifier | MGI:3832679 | Allele Type | Targeted |
| Gene | Chrna9 | Transmission | Germline |
| Strain of Origin | 129S4/SvJae | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The leucine at position 210 was mutated to a theonine (L210T) by changing the corresponding codon in exon 4 from TTG toACG. A floxed neomycin cassette was inserted into the NcoI restriction site within intron 3 for targeting purposes and was subsequently removed by crossing founder mice with cre transgenic mice. Quantitative PCR demonstrated expression levels of the mutant allele were similar to the wild-type allele. |
