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Allele : Itga3<tm1Hap> integrin alpha 3; targeted mutation 1, Harold A Chapman

Primary Identifier  MGI:3833130 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Itga3
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted around exon 3 and a FRT-flanked neomycin cassette was inserted downstream of exon 2. Founder mice were crossed with Flpe transgenic mice to remove the neomycin cassette. Gene expression in the absence of cre was unaffected as demonstrated by immunoblot analysis of homozygote kidney extracts. Cre-mediated removal of exon 3 will lead to an early termination codon in exon 4.
  • mutations:
  • Insertion
  • synonyms:
  • floxed alpha 3 intergrin,
  • floxed alpha 3 intergrin
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

15 Publication categories