| Help | About | Contact Us

Allele : Syne1<tm1.1Mcn> spectrin repeat containing, nuclear envelope 1; targeted mutation 1.1, Elizabeth M McNally

Primary Identifier	MGI:3834378	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Syne1
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Germ line, cre mediated recombination was used to remove the neo cassette and terminal coding exon. This deletes the transmembrane domain and short luminal sequence that contribute to the KASH domain

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
deltaKASH,
deltaKASH

earliestPublication:
Puckelwartz MJ, et al. (2009) Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice. Hum Mol Genet 18(4):607-20

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74728686

MouseMine