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Allele : Tg(SFTPC-EML4/ALK)502-4Hima transgene insertion 502-4, Hiroyuki Mano

Primary Identifier  MGI:3834680 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(SFTPC-EML4/ALK)502-4Hima
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The human SFTPC promoter was used to drive lung-specific expression of a flag-tagged human fusion generated in human non-small-cell lung cancer due to recurrent chromosome inversion, inv(2)(p21p23). Two lines were created (502-4 and 501-3) that exhibit identical tumor-forming activity. Line 502-4 was selected as the representative line. Line 502-4 carried 30 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • EML4-ALK,
  • EML4-ALK
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories