Primary Identifier | MGI:3834680 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(SFTPC-EML4/ALK)502-4Hima |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human SFTPC promoter was used to drive lung-specific expression of a flag-tagged human fusion generated in human non-small-cell lung cancer due to recurrent chromosome inversion, inv(2)(p21p23). Two lines were created (502-4 and 501-3) that exhibit identical tumor-forming activity. Line 502-4 was selected as the representative line. Line 502-4 carried 30 copies of the transgene. |