Primary Identifier | MGI:3836418 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Cdh5-cre)1Spe |
Strain of Origin | (C57BL/6J x 129S1/SvImJ)F1 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | 2.5 Kb of the Cdh5 promoter was fused to a cre recombinase gene and placed between two genomic insulators derived from the chicken gamma-globulin gene. When crossed with cre-reporter strains, cre expression was detected in the yolk sac and vasculature of E9.5-E10.5 conceptus, and in the liver of E15.5 fetuses. Nearly all adult blood cells from mice carrying this transgene are derived from progentiors that have expressed cre. |