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Allele : Tg(Cdh5-cre)1Spe transgene insertion 1, Nancy A Speck

Primary Identifier  MGI:3836418 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Cdh5-cre)1Spe
Strain of Origin  (C57BL/6J x 129S1/SvImJ)F1 Is Recombinase  true
Is Wild Type  false
molecularNote  2.5 Kb of the Cdh5 promoter was fused to a cre recombinase gene and placed between two genomic insulators derived from the chicken gamma-globulin gene. When crossed with cre-reporter strains, cre expression was detected in the yolk sac and vasculature of E9.5-E10.5 conceptus, and in the liver of E15.5 fetuses. Nearly all adult blood cells from mice carrying this transgene are derived from progentiors that have expressed cre.
  • mutations:
  • Insertion
  • synonyms:
  • Cdh5-cre,
  • VECad-Cre,
  • VEC-Cre,
  • VEC-Cre,
  • VECad-Cre,
  • Cdh5-cre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

1 Driven By

69 Publication categories