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Allele : Aurka<tm1.2Tvd> aurora kinase A; targeted mutation 1.2, Terry Van Dyke

Primary Identifier  MGI:3836423 Allele Type  Targeted
Attribute String  Null/knockout Gene  Aurka
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An frt and loxP flanked neo cassette was inserted into intron 1 and a third loxP site was inserted into intron 2 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 2. Deletion of exon 2 removes the ATg start site. Absence of protein expression was confirmed in blastocysts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • AurA<d2>,
  • AurA<d2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories