Primary Identifier | MGI:3834571 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(ATN1*)Drm21Stsu |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The transgene was engineered from BAC DRPLA18E that contains the human gene for ATN1 from a patient with dentatorubral-pallidoluysian atrophy (DRPLA) with a 76 CAG trinucleotide repeat within the gene. Three lines were created (lines Drm12, Drm21, and Drm22) with 78, 76 and 77 CAG repeats, respectively. |