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Allele : Clptq1<NZB/BlNJ> cellular lupus traits QTL 1; NZB/BlNJ

Primary Identifier	MGI:3835648	Allele Type	QTL
Gene	Clptq1	Strain of Origin	NZB/BlNJ
Is Recombinase	false	Is Wild Type	false

molecularNote

This allele confers increased thymus size, splenomegaly, increased B1a cell population and increased NKT cell population compared to C57BL/6J.

earliestPublication:
Loh C, et al. (2007) Dissociation of the genetic loci leading to b1a and NKT cell expansions from autoantibody production and renal disease in b6 mice with an introgressed new zealand black chromosome 4 interval. J Immunol 178(3):1608-17

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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